cenobamate will improve the level or impact of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep an eye on Closely. Look at a dose reduction of CYP2C19 substrates, as clinically correct, when utilised concomitantly with cenobamate.diazepam decreases levels of acetaminophen rectal by escalating metabolism. Insignificant/Im